Browsing by Author "Qualtiere, Louis"
Now showing items 1-8 of 8
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Activation of thymic T cells by MHC alloantigen can require syngeneic activated CD4 T cells and B cells as APC
Strutt, Tara Marlene (2005-04-05)An immunological mechanism to account for the regulation of peripheral self-reactive T cells, which escape central tolerance in the thymus, during the primary activation of naïve, foreign antigen-specific T cells remains ... -
Biophysical investigation of M-DNA
Wood, David Owen (2005-05-18)M-DNA is a complex formed between normal double-stranded DNA and the transition metal ions Zn2+, Ni2+, and Co2+ that is favoured by an alkaline pH. Previous studies have suggested that M-DNA formation involves replacement ... -
Electrochemical detection of interactions between DNA and various ligands
Muresan, Alina (2007-12-04)Antibodies specific for DNA, with varying degrees of sequence specificity, are common in many autoimmune diseases including systemic lupus erythematosus. The presence of anti-DNA antibodies is a useful determinant in ... -
Human dendritic cells and hepatitis C Virus
Landi, Abdolamir (2009-12)Dendritic cells (DCs) constitute a large family of immune cells with a dendritic morphology and a critical role in all aspects of an immune response and immune regulation, from immunogenicity to tolerance. One of the ... -
Immunology of BCG vaccination in mice : implications for tuberculosis vaccination and for the use of BCG as a recombinant vaccine vector
Power, Carl Andrew (2000-01-01)The effect of vaccination dose on the immune response of mice to Mycobacterium bovis Bacille Calmette-Guerin (BCG) was examined. To assess T helper cell-type 1 (Th1) and -type 2 (Th2) responses, a very sensitive ELISPOT ... -
In utero oral DNA immunization : induction of specific immunity in the second trimester ovine fetus
Tsang, Cemaine Happy (2007)Vaccination has proven a cost-effective method of managing infectious diseases, but attempts to develop an effective fetal vaccine have proven difficult due to the immaturity of the immune system and the propensity of the ... -
An in vitro study of the susceptibilities and growth dynamics of common ocular pathogens using five fluoroquinolones
Hedlin, Peter David Skarsgard (2005-08-29)Bacteria are responsible for up to 70% of all ocular infections including conjunctivitis, keratitis and endophthalmitis. If left untreated, a reduction of visual acuity, and in severe cases, sight loss, is possible. ... -
Monoclonal antibodies specific to the putative cancer signaling protein, Uev1A
Pelzer, Lindsay Jolene (2008)UEV1A and MMS2 are two human genes whose proteins share greater than ninety percent sequence identity. Both Uev1A and Mms2 are ubiquitin-conjugating enzyme variants (Uev) that lack the active cystine residue required for ...