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The Stetter reaction : synthesis of complex spiro Bis-indanes and studies on quaternary centre formation
This work covers recent advances in the Stetter reaction, including two novel domino Stetter reactions and preliminary studies on quaternary center formation via the intermolecular Stetter reaction. The N-heterocyclic ...
Thiopyran route to polypropionates : proline catalyzed aldol reactions of tetrahydro-4H-thiopyran-4-one
The thiopyran route to polypropionates is an attractive strategy that involves a stepwise iterative aldol homologation of tetrahydro-4H-thiopyran-4-one (I) with thiopyran aldehyde (II) followed by desulfurization to rapidly ...
Examination of Chemoselective N-Heterocyclic Carbene-Catalyzed Cross-Benzoin Reactions and Efforts Towards a Concise Total Synthesis of Sparteine
This thesis is broadly subdivided into two topics: the development and exploration of a methodology for catalyst-controlled chemoselective cross-benzoin reactions using N-heterocyclic carbenes, and efforts towards a concise ...
Enantioenriched amino ketones are convenient building blocks for a variety of synthetic transformations as well as important structural features in a wide array of natural products. N-heterocyclic carbene (NHC) catalyzed ...