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Antidepressant-Like Effects of Ketamine on Fear Conditioning and Extinction
The experience of chronic stress plays an important role in the pathogenesis of major depressive disorder. Prolonged stress induces a state of chronically elevated glucocorticoid exposure in the brain, which is neurotoxic ...
Examining Hippocampal Reelin Expression and Neural Plasticity in an Animal Model of Depression
Stress is an important risk factor for the development of clinical depression, yet little is known about the neurobiological mechanisms by which stress might promote depressive symptomatology. The brain is particularly ...