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Antidepressant-Like Effects of Ketamine on Fear Conditioning and Extinction
The experience of chronic stress plays an important role in the pathogenesis of major depressive disorder. Prolonged stress induces a state of chronically elevated glucocorticoid exposure in the brain, which is neurotoxic ...
Examining an Animal Model of Depression with Recurrent Depression-like Episodes
Depression is a complex psychiatric disorder. It is recognized as a cyclical disease with multiple episode relapses. Many preclinical animal models have been utilized to study the behavioral and neurobiological characteristics ...