Browsing Electronic Theses and Dissertations by Author "Eames, Brian"
Now showing items 1-9 of 9
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Bioprinting of Chondrocyte-Laden Hydrogel Constructs and their In-Vitro Characterization for Cartilage Tissue Engineering
You, Fu 1987- (2017-10-30)Abstract Articular cartilage lines the ends of bones, provides low friction and load bearing, and allows for efficient joint movement. Once damaged, articular cartilage has difficulty of repairing itself due to ... -
DEVELOPMENT OF ALGINATE NANOSPHERES AS A PROTEIN DELIVERY DEVICE FOR CARTILAGE TISSUE ENGINEERING
Yasmin, Farhana 1990- (2018-12-04)Delivery of bioactive proteins is a valuable strategy in cartilage tissue engineering (CTE) because of their ability to regulate the gene expression and extracellular matrix (ECM) production of engineered cartilage. This, ... -
Effects of a Third Year of Exercise Training Preceded by Two Years of Exercise Training with Isoflavone Supplementation on Bone in Postmenopausal Women
Abdulmula, Muhedeen Omar 1984- (2018-06-18)Osteoporosis is a chronic disease characterized by low bone mineral density (BMD) and micro-architectural deterioration and is especially prevalent in postmenopausal women. Soy isoflavones (i.e. “phytoestrogens”) have been ... -
Impacted third molars: using 3D imaging to investigate the etiology of a common oral health concern
Marchiori, Denver (2015-01-16)Third molar (M3) impaction is commonly observed in dental practice. While the causes of impaction are still not clearly understood, they appear to be multifactorial. Currently, an insufficient amount of space in the jaw ... -
Integrating biclustering techniques with de novo gene regulatory network discovery using RNA-seq from skeletal tissues
Ovens, Katie 1990-; 0000-0001-5956-7739 (2016-11-01)In order to improve upon stem cell therapy for osteoarthritis, it is necessary to understand the molecular and cellular processes behind bone development and the differences from cartilage formation. To further elucidate ... -
Linking new genes to an odontogenesis TP63-mediated gene regulatory network that is peripheral to jaw morphogenesis
Rostampour, Nasim 1988-; 0000-0002-6240-7012 (2018-02-27)Despite that teeth and jawbones can develop and evolve independently of each other, the genetic processes that independently regulate cranial and dental morphogenesis remain unclear. Previous microarray screens indicated ... -
Role of Hoxa2 and its Putative Downstream Target Htra1 in Osteogenic Differentiation of the Palatal Mesenchyme
Iyyanar, Paul Pown Raj 1987-; 0000-0003-0327-5395 (2018-04-26)Cleft palate is one of the most common structural birth defects in humans. Hoxa2 is the most anteriorly expressed gene of the homeobox family that define the anterior-posterior axis during embryonic development. Hoxa2 is ... -
The role of metal metabolism and heat shock protein genes on replicative lifespan of the budding yeast, Saccharomyces cerevisiae
Prusinkiewicz, Martin (2016-01-13)A variety of genes that influence aging have been identified in a broad selection of organisms including Saccharomyces cerevisiae (yeast), Caenorhabditis elegans (worms), Drosophila (fruit flies), Macaca Mulatta (rhesus ... -
The Impact of Rapamycin and Metformin on Genome Organization and Function in Normal Human Fibroblasts
Gillespie, Zoe Elizabeth 1993-; 0000-0003-1632-4504 (2017-01-24)For decades, dietary restriction (DR) has been documented to extend health and lifespan across numerous model organisms. Two compounds, rapamycin (an immuno-suppressant) and metformin (a drug used to treat type II diabetes) ...