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      Development and validation of fast and simple flow injection analysis-tandem mass spectrometry (FIA-MS/MS) for the determination of metformin in dog serum 

      El-Aneed, Anas; Arnason, Terra; Michel, Deborah; Gaunt, Matthew (Elsevier, 2015-03-25)
      A simple, fast and sensitive quantification method for the drug metformin in dog serum was developed using flow injection analysis (FIA)- tandem mass spectrometry (MS/MS). The method was fully validated according to ...
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      Mass Spectrometric Based Approaches in Urine Metabolomics and Biomarker Discovery 

      Khamis, Mona; Adamko, Darryl; El-Aneed, Anas (Wiley, 2015-04-15)
      Urine metabolomics has recently emerged as a prominent field for the discovery of non-invasive biomarkers that can detect subtle metabolic discrepancies in response to a specific disease or therapeutic intervention. Urine, ...
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      Hydrophilic interaction liquid chromatography–tandem mass spectrometry quantitative method for the cellular analysis of varying structures of gemini surfactants designed as nanomaterial drug carriers 

      Donkuru, McDonald; Michel, Deborah; Awad, Hanan; Katselis, George; El-Aneed, Anas (Elsevier, 2016-05-13)
      Diquaternary gemini surfactants have successfully been used to form lipid-based nanoparticles that are able to compact, protect, and deliver genetic materials into cells. However, what happens to the gemini surfactants ...
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      The Development of Novel Nanodiamond Based MALDI Matrices for the Analysis of Small Organic Pharmaceuticals 

      Chitanda, Jackson M; Zhang, Haixia; Pahl, Erica; Purves, Randy; El-Aneed, Anas (Springer, 2016-10-27)
      The utility of novel functionalized nanodiamonds (NDs) as matrices for matrix-assisted laser desorption ionization-mass spectrometry (MALDI-MS) is described herein. MALDI-MS analysis of small organic compounds (<1000 Da) ...
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      Establishment of Tandem Mass Spectrometric Fingerprint of Novel Antineoplastic Curcumin Analogues using Electrospray Ionization 

      Awad, Hanan; Das, Umashankar; Dimmock, Jonathan; El-Aneed, Anas (Wiley, 2015-07-30)
      RATIONALE: Curcumin analogues are antineoplastic agents, designed based on the structure of the spice turmeric with structural modifications aiming at enhancing potency. The goal is to identify the common tandem mass ...
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      Analysis of a Series of Chlorogenic Acid Isomers using Differential Ion Mobility and Tandem Mass Spectrometry 

      Willems, Jamie; Khamis, Mona, M.; Saeid, Waleed Mohammed; Purves, Randy, W.; Katselis, George; Low, Nicholas; El-Aneed, Anas (Elsevier, 2016-08-24)
      Chlorogenic acids are among the most abundant phenolics found in the human diet. Of these, the mono-caffeoylquinic acids are the predominant phenolics found in fruits, such as apples and pears, and products derived from ...
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      Comparison of accuracy and precision between multipoint calibration, single point calibration and relative quantification for targeted metabolomic analysis 

      Khamis, Mona M.; Klemm, Nancy; Adamko, Darryl; El-Aneed, Anas (SpringerLink, 2018-09)
      Targeted metabolomics requires accurate and precise quantification of candidate biomarkers, often through tandem mass spectrometric (MS/MS) analysis. Differential isotope labeling (DIL) improves mass spectrometric (MS) ...
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      Rapid and Simple Flow Injection Analysis-Tandem Mass Spectrometric (FIA-MS/MS) Method for the Quantification of Melphalan in Lipid-Based Drug Delivery System 

      Mohammed-Saeid, Waleed; Michel, Deborah; El-Aneed, Anas (Wiley, 2017-07-01)
      The use of the anticancer drug melphalan is limited due to its poor water solubility. To address such limitation, it is incorporated within a novel delivery system using β-cyclodextrin-gemini surfactants (18:1βCDg). Herein, ...
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      Development of a validated LC- MS/MS method for the quantification of 19 endogenous asthma/COPD potential urinary biomarkers 

      Khamis, Mona; Adamko, Darryl; El-Aneed, Anas (Elsevier, 2017-10-09)
      Obstructive airways inflammatory diseases sometimes show overlapping symptoms that hinder their early and correct diagnosis. Current clinical tests are tedious and are of inadequate specificity in special population such ...
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      Mass spectrometric approaches for the analysis of phytosterols in biological samples. 

      Gachumi, George N.; El-Aneed, Anas (ACS Publications, 2017-10-23)
      Plant sterols (phytosterols) are important structural components of plant cellular membranes and they play a major role during development and metabolism. They have health-associated benefits, especially in lowering blood ...
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      AuthorEl-Aneed, Anas (12)Khamis, Mona M. (6)Michel, Deborah (4)Chitanda, Jackson M (2)Katselis, George (2)Mansell, Holly (2)Purves, Randy W (2)||| (2)Adamko, Darryl (1)Adamko, Darryl (1)... View MoreSubjectalpha-synuclein (1)Asthma; COPD; HILIC-MS/MS; Targeted metabolomics; Urine; Validation (1)Chlorogenic acid isomers; Differential ion mobility; Tandem mass spectrometry (1)Dog serum; Flow injection analysis; MS/MS; Metformin; Quantification (1)Drug delivery nanoparticles; Gemini surfactants; HILIC chromatography; LC–MS/MS (1)Drug Delivery (1)Education (1)education (1)FIA-MS/MS, quantification, gemini surfactants, lipid-based gene delivery agents, cellular matrix (1)Flow Injection Analysis (1)... View MoreType
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      Date Issued2016 (4)2017 (4)2018 (4)2015 (3)2019 (1)2021 (1)
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