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      Comparison of accuracy and precision between multipoint calibration, single point calibration and relative quantification for targeted metabolomic analysis 

      Khamis, Mona M.; Klemm, Nancy; Adamko, Darryl; El-Aneed, Anas (SpringerLink, 2018-09)
      Targeted metabolomics requires accurate and precise quantification of candidate biomarkers, often through tandem mass spectrometric (MS/MS) analysis. Differential isotope labeling (DIL) improves mass spectrometric (MS) ...
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      The development of simple flow injection analysis tandem mass spectrometric methods for the cutaneous determination of peptide-modified cationic gemini surfactants used as gene delivery vectors. 

      Al-Dulaymi, Mays; Michel, Deborah; Chitanda, Jackson M; Badea, ildiko; El-Aneed, Anas (Elsevier, 2018-09-10)
      Diquaternary ammonium gemini surfactants are a class of non-viral gene delivery vectors, primarily studied for their dermal applications. However, their biological fate has rarely been investigated. In this work, we developed ...
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      Comparative analysis of creatinine and osmolality as urine normalization strategies in targeted metabolomics for the differential diagnosis of asthma and COPD 

      Khamis, Mona M.; Holt, Teagan; Awad, Hanan; El-Aneed, Anas; Adamko, Darryl (Springer Link, 2018-09-01)
      Introduction Urine is an ideal matrix for metabolomics investigation due to its non-invasive nature of collection and its rich metabolite content. Despite the advancements in mass spectrometry and 1H-NMR platforms in urine ...
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      The determination of gemini surfactants used as gene delivery agents in cellular matrix using validated tandem mass spectrometric method 

      El-Aneed, Anas (Elsevier, 2018-10-03)
      A simple, reliable flow injection analysis (FIA)-tandem mass spectrometric (MS/MS) method was developed for the determination of gemini surfactants, designated as 16-3-16, 16(Py)-S-2-S-(Py)16 and 16-7N(GK)-16, as gene ...

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      Author
      El-Aneed, Anas (4)
      Khamis, Mona M. (2)Adamko, Darryl (1)Adamko, Darryl (1)Al-Dulaymi, Mays (1)Awad, Hanan (1)Badea, ildiko (1)Chitanda, Jackson M (1)Holt, Teagan (1)Klemm, Nancy (1)... View MoreSubjectFIA-MS/MS, quantification, gemini surfactants, lipid-based gene delivery agents, cellular matrix (1)metabolomics; single point calibration; validation; quantification; differential isotope labeling, dansyl chloride (1)urine normalization, metabolomics, PLS-DA, creatinine, osmolality, targeted (1)... View MoreTypePostprint (4)Date Issued
      2018 (4)
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