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Evolutionary repression of chondrogenic genes in the vertebrate osteoblast
(Wiley, 2020-01-28)Gene expression in extant animals might reveal how skeletal cells have evolved over the past 500 million years. The cells that make up cartilage (chondrocytes) and bone (osteoblasts) express many of the same genes, but ... -
Fast oxygen dynamics as a potential biomarker for epilepsy
(Nature Research, 2018-12-18)Changes in brain activity can entrain cerebrovascular dynamics, though this has not been extensively investigated in pathophysiology. We assessed whether pathological network activation (i.e. seizures) in the Genetic Absence ... -
Prevalence and Determinants of Sinus Problems in Farm and Non-Farm Populations of Rural Saskatchewan, Canada
(MDPI, 2018-02-07)Although sinus problems have long been recognized as the most common respiratory symptoms associated with agricultural work, there is a scarcity of recent studies and/or reliable estimates as to the true prevalence or risk ... -
Development of a patient-centred, evidence-based and consensus-based discharge care bundle for patients with acute exacerbation of chronic obstructive pulmonary disease
(British Thoracic Society, 2018-01-30)Introduction: Hospital and emergency department discharge for patients with chronic obstructive pulmonary disease (COPD) is often poorly organised. We developed a patient-centred, evidence-based and consensus-based discharge ... -
The development, implementation and evaluation of clinical pathways for chronic obstructive pulmonary disease (COPD) in Saskatchewan: protocol for an interrupted times series evaluation
(BioMed Central, 2017-11-28)Introduction Hospital and emergency department discharge for patients with chronic obstructive pulmonary disease (COPD) is often poorly organised. We developed a patient-centred, evidence-based and consensusbased discharge ... -
Readability and Suitability of COPD Consumer Information
(Hindawi Publishing Corporation, 2017-08-29)Background. Information leaflets have been shown to positively or negatively impact adherence, depending on their content. The objective of this study was to perform an appraisal of the consumer information provided in ... -
Interpretation of Spirometry in Saskatchewan First Nations Adults
(Annals of the American Thoracic Society, 2018-10-01)The Canadian First Nations and Inuit communities bear a large burden of respiratory disease, with increased rates of smoking, respiratory infections, asthma, chronic obstructive lung disease, and hospitalizations (1). ...
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