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dc.contributor.advisorLaarveld, Bernarden_US
dc.contributor.advisorOlkowski, Andrew A.en_US
dc.creatorNain, Sukhbiren_US
dc.date.accessioned2008-02-29T19:57:37Zen_US
dc.date.accessioned2013-01-04T04:26:02Z
dc.date.available2009-03-05T08:00:00Zen_US
dc.date.available2013-01-04T04:26:02Z
dc.date.created2008en_US
dc.date.issued2008en_US
dc.date.submitted2008en_US
dc.identifier.urihttp://hdl.handle.net/10388/etd-02292008-195737en_US
dc.description.abstractA series of seven experiments were conducted to evaluate the risk of acute (sudden death syndrome; SDS) or chronic (congestive heart failure; CHF) heart failure associated with dietary over-supplementation of vitamin A, vitamin D3, vitamin E, vitamin C or cardiotoxic factors present in meat meal. The risk of heart failure associated with the above mentioned dietary factors was tested followed by gross, microscopic, ultrastructural and biochemical investigation for mechanisms associated with mentioned risk factors. Simultaneously, the molecular mechanisms underlying the deterioration of heart function in fast-growing commercial broilers were studied. Each compound was tested separately at a concentration higher than the recommended levels. The basic experimental unit comprised groups of 40 to 50 day old male broiler chickens at the start of experiment. Lowered thermal brooding temperature protocol, an approach resulting in clinical manifestation of heart failure in practically all broilers predisposed to heart disease, was used. Broilers fed the vitamin D3 enriched diet were 2.5 fold more likely to succumb to acute heart failure (pen_US
dc.language.isoen_USen_US
dc.subjectHeart Failureen_US
dc.subjectMeat Mealen_US
dc.subjectBroileren_US
dc.subjectVitaminen_US
dc.subjectOxidative Stressen_US
dc.titleStudy on dietary factors pertinent to the pathogenesis of heart failure in fast-growing commercial broilersen_US
thesis.degree.departmentAnimal and Poultry Scienceen_US
thesis.degree.disciplineAnimal and Poultry Scienceen_US
thesis.degree.grantorUniversity of Saskatchewanen_US
thesis.degree.levelDoctoralen_US
thesis.degree.nameDoctor of Philosophy (Ph.D.)en_US
dc.type.materialtexten_US
dc.type.genreThesisen_US
dc.contributor.committeeMemberDrew, Murray D.en_US
dc.contributor.committeeMemberClassen, Henry L. (Hank)en_US
dc.contributor.committeeMemberCherian, Gitaen_US
dc.contributor.committeeMemberBuchanan, Fiona C.en_US
dc.contributor.committeeMemberAlcorn, Janeen_US
dc.contributor.committeeMemberWojnarowicz, Chrisen_US


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