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dc.contributor.advisorBegg, Robert Williamen_US
dc.creatorBurton, Albert Fredericken_US
dc.date.accessioned2010-09-08T10:07:32Zen_US
dc.date.accessioned2013-01-04T04:56:59Z
dc.date.available2011-09-15T08:00:00Zen_US
dc.date.available2013-01-04T04:56:59Z
dc.date.created1958en_US
dc.date.issued1958en_US
dc.date.submitted1958en_US
dc.identifier.urihttp://hdl.handle.net/10388/etd-09082010-100732en_US
dc.description.abstractTransplanted tumors have been widely used in cancer research for half a century. There is some evidence, however, that transplanted tumors differ in certain respects from tumors which occur spontaneously. This is particularily evident in chemotherapy screening trials which have revealed spontaneous tumors to be quite unresponsive to numerous agents which inhibit the growth of transplanted tumors. An investigation was therefore undertaken of some biochemical properties of spontaneous mammary tumors in an inbred strain of mice, and the transplanted tumors derived from these. Tumors were analyzed for several constituents, and the relative rates of incorporation of several radioactive compounds were determined. Some factors influencing the latent period, growth rates and response to cortisone therapy of these tumors were observed.en_US
dc.language.isoen_USen_US
dc.titleThe biochemical variation in tumors during transplantationen_US
thesis.degree.departmentCancer Researchen_US
thesis.degree.disciplineCancer Researchen_US
thesis.degree.grantorUniversity of Saskatchewanen_US
thesis.degree.levelDoctoralen_US
thesis.degree.nameDoctor of Philosophy (Ph.D.)en_US
dc.type.materialtexten_US
dc.type.genreThesisen_US
dc.contributor.committeeMemberStich, H. F.en_US
dc.contributor.committeeMemberMcMurray, W. C.en_US


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