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      • HARVEST
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      Interaction of growth hormone and insulin-like growth factor-I in the control of steroidogenesis by cultured porcine granulosa cells

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      Date
      1996-01-01
      Author
      Xu, Yongping
      Type
      Thesis
      Degree Level
      Doctoral
      Metadata
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      Abstract
      In order to better understand the factors controlling or modulating ovarian function, and in an attempt to develop a way to increase ovulation rate in gilts, the effects of metabolic hormones such as growth hormone (GH), insulin or prolactin and growth factors such as insulin-like growth factor I or II (IGF-I or IGF-II) on steroidogenesis in cultured porcine granulosa cells were investigated with emphasis on the interaction between GH and IGFs. Experiment one was conducted to examine the influence of metabolic hormones and growth factors on progesterone and estradiol secretion by porcine granulosa cells in culture, and to determine the possible site(s) of action of these agents on steroidogenesis. Both IGF-I and IGF-II increased (P $
      Degree
      Doctor of Philosophy (Ph.D.)
      Department
      Animal and Poultry Science
      Program
      Animal and Poultry Science
      Committee
      Thacker, Philip A.
      Copyright Date
      January 1996
      URI
      http://hdl.handle.net/10388/etd-10202004-235736
      Collections
      • Graduate Theses and Dissertations
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