Zinc and taurine interactions in maternofetal metabolism
Date
1998-01-01
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Journal ISSN
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Publisher
ORCID
Type
Degree Level
Doctoral
Abstract
It was proposed that zinc and taurine interact in vivo to influence reproductive outcome in the rat. The effect of taurine deficiency induced by guanidinoethyl sulfonate (GES), a taurine transport antagonist, on fetal development was examined. Female Sprague-Dawley rats were mated overnight and assigned to 1 of 4 treatments through gestation. Animals received taurine-restricted diet and 0.5% 1.0% or 2.0% GES in drinking water. Control animals received taurine-adequate diet and no GES. Taurine deficiency produced a sharp decline in maternal and fetal liver taurine (p
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Degree
Doctor of Philosophy (Ph.D.)
Department
Nutrition
Program
Nutrition