Repository logo
 

Interaction of growth hormone and insulin-like growth factor-I in the control of steroidogenesis by cultured porcine granulosa cells

Date

1996-01-01

Journal Title

Journal ISSN

Volume Title

Publisher

ORCID

Type

Degree Level

Doctoral

Abstract

In order to better understand the factors controlling or modulating ovarian function, and in an attempt to develop a way to increase ovulation rate in gilts, the effects of metabolic hormones such as growth hormone (GH), insulin or prolactin and growth factors such as insulin-like growth factor I or II (IGF-I or IGF-II) on steroidogenesis in cultured porcine granulosa cells were investigated with emphasis on the interaction between GH and IGFs. Experiment one was conducted to examine the influence of metabolic hormones and growth factors on progesterone and estradiol secretion by porcine granulosa cells in culture, and to determine the possible site(s) of action of these agents on steroidogenesis. Both IGF-I and IGF-II increased (P $

Description

Keywords

Citation

Degree

Doctor of Philosophy (Ph.D.)

Department

Animal and Poultry Science

Program

Animal and Poultry Science

Advisor

Part Of

item.page.relation.ispartofseries

DOI

item.page.identifier.pmid

item.page.identifier.pmcid