Synthesis of fluorinated cannabinoid derivatives; Towards PET radiotracers for imaging the cannabinoid receptor
Date
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
ORCID
Type
Thesis
Degree Level
Doctoral
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Description
Keywords
endocannabinoid system, cannabinoid receptors, endogenous ligands, CB1R, neurotransmitters, neuropsychiatric disorders, drug target, biomarker, functional imaging, positron emission tomography, PET, fluorinated analogs, tetrahydrocannabinol, THC, cannabidiol, CBD, cannabicyclol, CBL, cannabichromene, CBC, Cannabis sativa, PET tracers, radiolabeling, 18F, in vivo imaging, biological activity, cell models, rodents, ligands, psychotropic effects, orthosteric agonists, GAT211, positive allosteric modulators, PAMs, structural modification, biological assays, partial agonists, biodistribution, microPET imaging, dynamic PET/CT imaging, radiotracer, brain uptake, rimonabant, CB1R antagonist, selective binding, CB1R modulators
Citation
Degree
Doctor of Philosophy (Ph.D.)
Department
Chemistry
Program
Chemistry