Coupling field and laboratory studies of immunity and infection in zoonotic hosts
Date
2023
Authors
Becker, Daniel J.
Banerjee, Arinjay
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Elsevier
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Article
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Abstract
The COVID-19 pandemic and discovery of SARS-CoV-2-like viruses in Rhinolophus bats has reinforced the need to identify wildlife sources of zoonotic pathogens and to forecast where and when spillover to humans is likely to occur. Although we have long recognised that most emerging infectious diseases, especially viral infections, originate in wildlife, the global virome remains poorly characterised. Growing quantities of host–virus association data and advancements in statistical modelling are now facilitating our ability to predict probable wildlife hosts and prioritise field sampling to uncover novel virus diversity. How best to follow such species-level predictions for downstream insights most relevant to the risk of zoonotic spillover is an outstanding challenge.
Description
Keywords
SARS-CoV-2, Rhinolophus, global virome
Citation
Becker, D. J., & Banerjee, A. (2023). Coupling field and laboratory studies of immunity and infection in zoonotic hosts. The Lancet. Microbe, 4(5), e285–e287. https://doi.org/10.1016/S2666-5247(23)00032-0
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DOI
https://doi.org/10.1016/S2666-5247(23)00032-0