Statistical power of epidemiological studies of low dose levels of ionizing radiation and cancer
| dc.contributor.advisor | Khan, Shahhedul | |
| dc.contributor.advisor | Feng, Cindy | |
| dc.contributor.advisor | Cranmer-Sargison, Gavin | |
| dc.contributor.committeeMember | Pahwa, Punam | |
| dc.contributor.committeeMember | Li, Longhai | |
| dc.contributor.committeeMember | Guo, Xulin | |
| dc.creator | Soltani Farsani, Jafar | |
| dc.date.accessioned | 2020-05-04T15:47:16Z | |
| dc.date.available | 2020-05-04T15:47:16Z | |
| dc.date.created | 2020-04 | |
| dc.date.issued | 2020-05-04 | |
| dc.date.submitted | April 2020 | |
| dc.date.updated | 2020-05-04T15:47:17Z | |
| dc.description.abstract | The purpose of this research is to inspect the statistical power of studies that investigate the effects of low dose ionizing radiation on the incidence of/mortality from cancer. I use a procedure proposed in a similar study to handle a problem regarding the incidence of childhood leukemia from background ionizing radiation. I study this procedure critically and make some adjustments to make its performance better. I also propose some substitute methods to the methods proposed in the aforementioned reference in order to calculate the power. In addition, I propose other methods not used in the study mentioned above. I evaluate the efficiency of my proposed approaches using simulated data. The improved method can be applied to the National Dose Registry of Canada (NDR) to produce the power curves. The outcomes then can be used to propose the most suitable study design. Some of the previous epidemiological studies based on NDR can also be evaluated in terms of power. | |
| dc.format.mimetype | application/pdf | |
| dc.identifier.uri | http://hdl.handle.net/10388/12819 | |
| dc.subject | Statistical power | |
| dc.subject | Ionizing radiation | |
| dc.subject | Score test statistic | |
| dc.title | Statistical power of epidemiological studies of low dose levels of ionizing radiation and cancer | |
| dc.type | Thesis | |
| dc.type.material | text | |
| thesis.degree.department | School of Public Health | |
| thesis.degree.discipline | Biostatistics | |
| thesis.degree.grantor | University of Saskatchewan | |
| thesis.degree.level | Masters | |
| thesis.degree.name | Master of Science (M.Sc.) |