SYNTHESIS OF 2H-1,14.-BENZOTHIAZINES AND RELATED COMPOUNDS
Date
1965
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
ORCID
Type
Degree Level
Masters
Abstract
A variety of reasons exist for making an invest-igation into the chemistry of cyclic hydroxamic acids, especially% those possessing a 2H-1,4-benzothiazine nucleus. These reasons are discussed below.
Cyclic hydroxamic acids, as the name suggests, possess a hydroxamate group which exists in an equilibrium between the two forms, as shown (I).
The group is strongly acidic in natures being sol-uble in relatively weak bases such as sodium bicarbonate. The hydroxamic acid group is able to form chelates with metals. The structure of a divalent metal chelate is thought to be as shown (II)
Description
Keywords
Cyclic hydroxamic acids
Citation
Degree
Master of Science (M.Sc.)
Department
Pharmacy