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Retinal blood vessel segmentation: methods and implementations

dc.contributor.advisorKo, Seokbum
dc.contributor.committeeMemberChen, Li
dc.contributor.committeeMemberChung, Chi Yung
dc.contributor.committeeMemberChang, Gap Soo
dc.creatorJiang, Zhexin 1992-
dc.creator.orcid0000-0002-7670-0826
dc.date.accessioned2017-08-23T17:29:59Z
dc.date.available2017-08-23T17:29:59Z
dc.date.created2017-08
dc.date.issued2017-08-23
dc.date.submittedAugust 2017
dc.date.updated2017-08-23T17:30:05Z
dc.description.abstractSince the retinal blood vessel has been acknowledged as an indispensable element in both ophthalmological and cardiovascular disease diagnosis, the accurate segmentation of the retinal vessel tree has become the prerequisite step for automatic or computer-aided diagnosis systems. This thesis, therefore, has investigated different works of image segmentation algorithms and techniques, including unsupervised and supervised methods. Further, the thesis has developed and implemented two systems of the accurate retinal vessel segmentation. The methodologies explained and analyzed in this thesis, have been selected as the most efficient approaches to achieve higher precision, better robustness, and faster execution speed, to meet the strict standard of the modern medical imaging. Based on the intensive investigation and experiments, this thesis has proposed two outstanding implementations of the retinal blood vessel segmentation. The first implementation focuses on the fast, accurate and robust extraction of the retinal vessels using unsupervised techniques, by applying morphology-based global thresholding to draw the retinal venule structure and centerline detection to extract the capillaries. Besides, this system has been designed to minimize the computing complexity and to process multiple independent procedures in parallel. The second proposed system has especially focused on robustness and accuracy in regardless of execution time. This method has utilized the full convolutional neural network trained from a pre-trained semantic segmentation model, which is also called the transfer deep learning. This proposed method has simplified the typical retinal vessel segmentation problem from full-size image segmentation to regional vessel element recognition. Both of the implementations have outperformed their related works and have presented a remarkable scientific value for future computer-aided diagnosis applications. What’s more, this thesis is also a research guide which provide readers with the comprehensive knowledge on how to research on the task of retinal vessel segmentation.
dc.format.mimetypeapplication/pdf
dc.identifier.urihttp://hdl.handle.net/10388/8037
dc.subjectRetinal blood vessel segmentation
dc.subjectRetinal images
dc.subjectDeep learning
dc.subjectFully convolutional network
dc.subjectTransfer learning
dc.subjectPre-trained model
dc.subjectMorphological processing
dc.subjectDoOG filter
dc.subjectAutomated analysis
dc.subjectThresholding
dc.titleRetinal blood vessel segmentation: methods and implementations
dc.typeThesis
dc.type.materialtext
thesis.degree.departmentElectrical and Computer Engineering
thesis.degree.disciplineElectrical Engineering
thesis.degree.grantorUniversity of Saskatchewan
thesis.degree.levelMasters
thesis.degree.nameMaster of Science (M.Sc.)

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