Design, Synthesis, and Preclinical Evaluation of Alpha-Synuclein Binding 19/18Fluorine Labelled Bifunctional/Trifunctional Agents as Potential Positron Emission Tomography Imaging Probes For Parkinson’s Disease
Date
2023-05-05
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
ORCID
0000-0002-7655-665X
Type
Thesis
Degree Level
Doctoral
This item is under an embargo.
Access to the abstract and all associated documents will not be permitted until 2025-05-05.
Description
Keywords
Microsomal metabolism, Method validation, Parkinson’s disease, Positron Emission Tomography, Imaging probe design, Alpha-synuclein, Enzyme kinetics, Fluorine-18, Pharmacophore Modelling, Biodistribution, Radiolabelling
Citation
Degree
Doctor of Philosophy (Ph.D.)
Department
Chemistry
Program
Chemistry