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Design, Synthesis, and Preclinical Evaluation of Alpha-Synuclein Binding 19/18Fluorine Labelled Bifunctional/Trifunctional Agents as Potential Positron Emission Tomography Imaging Probes For Parkinson’s Disease

Date

2023-05-05

Journal Title

Journal ISSN

Volume Title

Publisher

ORCID

0000-0002-7655-665X

Type

Thesis

Degree Level

Doctoral

This item is under an embargo.

Access to the abstract and all associated documents will not be permitted until 2025-05-05.

Description

Keywords

Microsomal metabolism, Method validation, Parkinson’s disease, Positron Emission Tomography, Imaging probe design, Alpha-synuclein, Enzyme kinetics, Fluorine-18, Pharmacophore Modelling, Biodistribution, Radiolabelling

Citation

Degree

Doctor of Philosophy (Ph.D.)

Department

Chemistry

Program

Chemistry

Part Of

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DOI

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