Burgess, Ian2020-07-062020-07-064/1/2020Erick Lins, Stuart Read, Bipinlal Unni, Scott M. Rosendahl and Ian J. Burgess, (2020) Microsecond Resolved Infrared Spectroelectrochemistry Using Dual Frequency Comb IR Lasers. Analytical Chemistry. 92, 6241-6244http://hdl.handle.net/10388/12909This document is the unedited Author’s version of a Submitted Work that was subsequently accepted for publication in Analytical Chemistry, copyright © American Chemical Society after peer review.A dual infrared frequency comb spectrometer with heterodyne detection has been used to perform time resolved electrochemical attenuated total reflectance surface enhanced infrared absorption spectroscopy (ATR-SEIRAS). The measurement of the potential dependent desorption of a monolayer of a pyridine derivative (4-dimethylaminopyridine, DMAP) with time resolution as high as 4 μs was achieved without the use of step-scan interferometry. An analysis of the detection limit of the method as a function of both time resolution and measurement co-additions is provided and compared to step-scan experiments of an equivalent system. Dual frequency comb spectroscopy is shown to be highly amenable to time-resolved ATR-SEIRAS. Microsecond resolved spectra can be obtained with high spectral resolution and fractional monolayer detection limits in a total experimental duration that is two orders of magnitude less than the equivalent step-scan experiment.enPreprint10.1021/acs.analchem.0c00260