Chilibeck, Philip D.2008-06-042013-01-042009-06-052013-01-04200820082008http://hdl.handle.net/10388/etd-06042008-104302This thesis evaluated supplementation with two components of flaxseed during exercise training on inflammation in older adults.Experiment 1: This experiment assessed secoisolariciresinol diglucoside (SDG) supplementation during aerobic exercise training on inflammation in older adults. Methods: One hundred subjects aged 50y or older were randomized to receive either SDG or placebo before completing a 6-month walking program. Fasting concentrations of interleukin-6 and tumor necrosis factor-á, glucose, triacylglycerol (TAG), high density lipoprotein (HDL), low density lipoprotein, and total cholesterol as well as leukocyte cell count were measured every two months while body composition, resting blood pressure, and a composite Z-score of six metabolic syndrome risk factors were assessed at baseline and 6 months. Results: Men on placebo increased metabolic syndrome composite Z-score (pen-USSecoisolariciresinol DiglucosideAlpha-Linolenic AcidMetabolic SyndromeSarcopeniaExerciseInterleukin-6Tumor Necrosis Factor-Alphatext