Browsing by Author "Kalynchuk, Lisa"
Now showing items 1-14 of 14
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Brainstem kindling: seizure development and functional consequences
Lam, Ann (2011-03)This dissertation explores the role of brainstem structures in the development and expression of generalized tonic-clonic seizures. The functional consequences of brainstem seizures are investigated using the kindling ... -
Effects of protein-energy malnutrition on outcome from global cerebral ischemia
Prosser-Loose, Erin Jane (2010-08)The goal of my thesis was to elucidate the impact of protein-energy malnutrition (PEM, a condition commonly found in aging stroke patients) on outcomes from global ischemia. I first examined the hypothesis that PEM will ... -
Examining an Animal Model of Depression with Recurrent Depression-like Episodes
Lebedeva, Katherina A 1988-; 0000-0003-4166-7963 (2017-01-12)Depression is a complex psychiatric disorder. It is recognized as a cyclical disease with multiple episode relapses. Many preclinical animal models have been utilized to study the behavioral and neurobiological characteristics ... -
Examining Hippocampal Reelin Expression and Neural Plasticity in an Animal Model of Depression
Fenton, Erin (2013-11-22)Stress is an important risk factor for the development of clinical depression, yet little is known about the neurobiological mechanisms by which stress might promote depressive symptomatology. The brain is particularly ... -
Examining Relations Between Stress Generation and Inferential Style At Micro and Macro Levels
Scallion, Laura 1986- (2017-05-15)The generation of stress, or the amount of life events that are influenced at least partially by individuals, is a phenomenon that was initially observed in individuals with depressive symptoms. Stress generation (SG) is ... -
Examining the effects of a Daily Writing Intervention on Perceived Social Support and Depressive Symptoms
Saint, Daniel Sebastian 1986-; 0000-0001-5446-5696 (2018-12-03)Clinical depression is an illness that affects millions of people worldwide (Kessler et al., 2003; Weissman et al., 1996). It accounts for a large portion of health burden worldwide and greatly impacts the lives of many ... -
Fear Learning as a Component of a Depressive Phenotype in Rodents
Marks, Wendie (2014-06-23)Depression is a complex psychiatric illness that affects a large proportion of the population. Many researchers make use of preclinical animal models to study the behavioural and neurobiological characteristics of this ... -
Lateral Biases in Attention and Working Memory Systems
Szelest, Izabela (2014-07-25)Neurologically healthy individuals misbisect their visual space by erring towards the left. This misreprentation has been attributed to the right hemisphere dominance in processing of spatial information. Lateral biases ... -
Non-suicidal self-injury : the associations among emotional, parental, and peer influences
Sharp, Maegan (2014-03-31)Non-suicidal self-injury (NSSI) is a complex and dangerous set of behaviours that has been gaining increased research attention in recent years. Although existing research indicates that NSSI is prevalent among both ... -
The Role of Phosphorylated CREB in the Preferential Recruitment of Immature Dentate Granule Neurons into Learning and Memory Circuitry
Guskjolen, Axel (2011-12-21)Adult hippocampal neurogenesis has been linked with learning and memory in mammalian species (including humans). Recent work has demonstrated a critical period following the birth of new hippocampal neurons during which ... -
Strategy use and basic arithmetic cognition in adults
Metcalfe, Arron (2010-10)Arithmetic cognition research was at one time concerned mostly with the representation and retrieval of arithmetic facts in memory. More recently it was found that memory retrieval does not account for all single digit ... -
Stress and depression discourses on self-help websites : what is their relation in the online context?
Valiakalayil, Agitha (2015-10-09)Stress and depression are popular and powerful terms within the mental health field. Although the relation between the two terms has been discussed and investigated in lay and scientific discourse, less is known about how ... -
Temporal examination of novel transcription factors in the cell body response of sensory neurons to injury
Hasmatali, Jovan CD 1983-; 0000-0002-1299-4538 (2017-01-05)Primary sensory neurons in dorsal root ganglia (DRG) undergo a cell body response after injury, where the neurons activate genetic growth programs with the goal of regenerating new axons. Transcriptional regulators are key ... -
The crucial role of reelin in a preclinical model of depression
Allen, Joshua 1993- (2018-01-05)Depression is a complex psychiatric disorder characterized by a cyclical disease course with repeated episode relapses. Rats treated for 21 days with corticosterone (CORT), a well characterized model of depression, exhibit ...