Now showing items 1-4 of 4
Antidepressant-like Effects of Peripheral Reelin Administration in a Preclinical Model of Depression
Depression is a serious psychiatric disorder characterized by a range of debilitating symptoms. Long-term exposure to stress is a significant risk factor for the onset and maintenance of depression. Rats exposed to repeated ...
Assessing the role of the hippocampus in amygdala kindled fear : an analysis of environmental habituation
Amygdala kindling is commonly used to study the mechanisms involved in epileptogenesis, with long-term amygdala kindling providing a useful model of the behavioural disturbances— such as heightened anxiety— that can occur ...
Aberrant structural and functional plasticity in the adult hippocampus of amygdala kindled rats
Amygdala kindling is commonly used to study the neural mechanisms of temporal lobe epilepsy and its behavioral consequences. The repetitive seizure activity that occurs during kindling is thought to induce an extensive ...
Examining Hippocampal Reelin Expression and Neural Plasticity in an Animal Model of Depression
Stress is an important risk factor for the development of clinical depression, yet little is known about the neurobiological mechanisms by which stress might promote depressive symptomatology. The brain is particularly ...