Browsing Electronic Theses and Dissertations by Author "Tabel, Henry"
Now showing items 1-10 of 10
-
An analysis of the molecular regulation of tumor necrosis factor-alpha expression in human mast cells
Yue, Binbin (2000-03)The objective of this study was to analyze the molecular regulation of tumour necrosis factor-alpha (TNF-α) gene expression in human cells. Allergic diseases (e.g., asthma) comprise one of the most prominent medical ... -
Complement receptor 2 (CR2/CD21) in experimental African trypanosomiasis
Munasinghe, Lilani Indika (2009)African trypanosomes are protozoan blood parasites that infect both humans and livestock. BALB/c mice are highly susceptible to experimental infections by Trypanosoma congolense while C57BL/6 mice are relatively resistant, ... -
Genetics of resistance to Trypanosoma congolense infection
Ogunremi, Oladele Alabi (1993-01-01)The principal goals of this investigation were (1) to study the inheritance of resistance to Trypanosoma congolense in mice, (2) to develop an assay for assessing the activity of the murine alternative pathway of complement ... -
HER-2/neu-targeted immunoprevention of breast cancer
Sas, Sheena Emm (2007-03-27)Improvements in the use of traditional breast cancer therapies have improved the overall survival of women with early stage disease. Remarkable advances in research have created a unique opportunity for developing active ... -
IL-10-differentiated dendritic cells treatment for Experimental Autoimmune Encephalomyelitis (EAE), a model of human Multiple Sclerosis
Xie, Siyuan (2010-05)Multiple sclerosis is a chronic autoimmune neurological disease characterized by inflammatory cell infiltration and demyelination in the central nervous system (CNS). It is considered to be mediated by Th1 and Th17 immune ... -
Low dose BCG vaccination in mice : immune responses and implications for tuberculosis control
Gebreyohannes, Tadele Kiros (2007)The outcome of an infection is often determined by the qualitative nature of the immune response generated against the infectious agent. Various intracellular pathogens, including those that cause leprosy, tuberculosis, ... -
Macrophage cytokines as correlate of differential resistance to African trypanosomiasis
Kaushik, Radhey Shyam (1999-01-01)BALB/c mice are susceptible to 'T. congolense' infection as they succumb within 8.4 ± 0.5 days while C57Bl/6 mice are relatively resistant as they survive up to 163 ± 12 days. Evidence suggests that macrophages play a ... -
Molecular characterization of streptococcus uberis CAMP factor, lactoferrin binding protein and their upstream genes
Jiang, Min (1996-01-01)The gene coding for the CAMP factor from a strain of Streptococcus uberis (S. uberis ) was cloned in E. coli. Chromosomal DNA from S. uberis was used to construct a gene library in plasmid pTZ18R and six CAMP-reaction ... -
Phagocytosis of Trypanosoma congolense by macrophages : the role of IgM antibody to variant surface glycoprotein (VSG)
Pan, Wanling (2005-03-01)Trypanosoma congolense is a single-cell blood parasite and an important pathogen causing African trypanosomiasis, also called n’gana, in livestock. N’gana in cattle is a chronic disease associated with anemia, cachexia ... -
Role of cytokines in resistance to African trypanosomes
Uzonna, Jude Ezeh (1998-01-01)The expression and role of cytokines in resistance to experimental Trypanosoma congolense infections in the highly susceptible BALB/c and relatively resistant C57BL/6 mice was studied. Higher levels of IL-4, IL-10 and IFN-ã ...