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      Mass Spectrometric Based Approaches in Urine Metabolomics and Biomarker Discovery 

      Khamis, Mona; Adamko, Darryl; El-Aneed, Anas (Wiley, 2015-04-15)
      Urine metabolomics has recently emerged as a prominent field for the discovery of non-invasive biomarkers that can detect subtle metabolic discrepancies in response to a specific disease or therapeutic intervention. Urine, ...
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      Analysis of a Series of Chlorogenic Acid Isomers using Differential Ion Mobility and Tandem Mass Spectrometry 

      Willems, Jamie; Khamis, Mona, M.; Saeid, Waleed Mohammed; Purves, Randy, W.; Katselis, George; Low, Nicholas; El-Aneed, Anas (Elsevier, 2016-08-24)
      Chlorogenic acids are among the most abundant phenolics found in the human diet. Of these, the mono-caffeoylquinic acids are the predominant phenolics found in fruits, such as apples and pears, and products derived from ...
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      Comparison of accuracy and precision between multipoint calibration, single point calibration and relative quantification for targeted metabolomic analysis 

      Khamis, Mona M.; Klemm, Nancy; Adamko, Darryl; El-Aneed, Anas (SpringerLink, 2018-09)
      Targeted metabolomics requires accurate and precise quantification of candidate biomarkers, often through tandem mass spectrometric (MS/MS) analysis. Differential isotope labeling (DIL) improves mass spectrometric (MS) ...
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      Development of a validated LC- MS/MS method for the quantification of 19 endogenous asthma/COPD potential urinary biomarkers 

      Khamis, Mona; Adamko, Darryl; El-Aneed, Anas (Elsevier, 2017-10-09)
      Obstructive airways inflammatory diseases sometimes show overlapping symptoms that hinder their early and correct diagnosis. Current clinical tests are tedious and are of inadequate specificity in special population such ...
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      Comparative analysis of creatinine and osmolality as urine normalization strategies in targeted metabolomics for the differential diagnosis of asthma and COPD 

      Khamis, Mona M.; Holt, Teagan; Awad, Hanan; El-Aneed, Anas; Adamko, Darryl (Springer Link, 2018-09-01)
      Introduction Urine is an ideal matrix for metabolomics investigation due to its non-invasive nature of collection and its rich metabolite content. Despite the advancements in mass spectrometry and 1H-NMR platforms in urine ...
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      Quantitative determination of potential urine biomarkers of respiratory illnesses using new targeted metabolomic approach 

      Khamis, Mona M. (Elsevier, 2019-01-24)
      The diagnosis of asthma and chronic obstructive pulmonary disease (COPD) can be challenging due to the overlap in their clinical presentations in some patients. There is a need for a more objective clinical test that can ...

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      Author
      Khamis, Mona M. (6)
      El-Aneed, Anas (5)Adamko, Darryl (1)Adamko, Darryl (1)Adamko, Darryl (1)Adamko, Darryl (1)Awad, Hanan (1)Holt, Teagan (1)Katselis, George (1)Klemm, Nancy (1)... View MoreSubjectAsthma; COPD; HILIC-MS/MS; Targeted metabolomics; Urine; Validation (1)Chlorogenic acid isomers; Differential ion mobility; Tandem mass spectrometry (1)Metabolome, Urine, Untargeted, Targeted, Biomarker, Mass Spectrometry (1)metabolomics; single point calibration; validation; quantification; differential isotope labeling, dansyl chloride (1)urine normalization, metabolomics, PLS-DA, creatinine, osmolality, targeted (1)... View MoreTypePostprint (6)Date Issued2018 (2)2015 (1)2016 (1)2017 (1)2019 (1)
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