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Item DOMESTIC PRODUCTION OF Mo-99 AND Ac-225 USING COMMERCIAL PWR AND FAST EXPERIMENTAL REACTOR JOYO IN JAPAN(2023) Takaki, Naoyuki; Iwahashi, Daiki; Sasaki, Yuto; Maeda, ShigetakaThe production technology of medical radioisotopes (RI) using existing nuclear fission reactors has been studied to improve/achieve their domestic preparedness in Japan. The target nuclides currently considered in our project are Mo/Tc which is the most commonly used ones in medical diagnosis and Ac-225 which is recently known as effective alpha emitting nuclide for targeted alpha-particle therapy. Existing fission reactors, PWRs and Joyo in Japan, have potentials to work as excellent facilities for medical isotope production, as by-products of heat/electricity generation without consuming electricity and needs for new plant construction.