Toll-Like Receptor 10 in Human Lungs
Date
2022
Authors
Fowler, Brooke
Singh, Baljit
Aulakh, Gurpreet
Journal Title
Journal ISSN
Volume Title
Publisher
ORCID
Type
Poster Presentation
Degree Level
Abstract
The biggest infectious disease outbreaks have been respiratory diseases, which are a leading
cause to death and disability in humans. Though the use of antibiotics has helped greatly, challenges occur due to the evolution of anti-microbial resistance. Fortunately, the body has an innate immune system that is the primary response when an infection invades the lungs. Toll-like receptors are important for this primary response. They recognize pathogens and initiate a cascade of events to activate an inflammatory response. Toll-like receptor 10, also known as TLR10, has a unique anti-inflammatory function. This is different compared to the other TLRs, since they have pro-inflammatory properties. TLR10 is the latest TLR to be discovered, therefore
little data can be found on its expression and very little is known about its function.
Description
Keywords
respiratory disease, toll-like receptors