Oxazolium Salts as Organocatalysts for the Umpolung of Aldehydes
| dc.contributor.author | Garapati, Venkata Krishna Rao | |
| dc.contributor.author | Gravel, Michel | |
| dc.date.accessioned | 2020-12-21T16:52:28Z | |
| dc.date.available | 2020-12-21T16:52:28Z | |
| dc.date.issued | 10/1/2018 | |
| dc.description.abstract | Oxazolium salts were successfully employed for the first time as organocatalysts for benzoin, Stetter, and redox esterification reactions. An N-mesityl oxazolium salt catalyzed homobenzoin reaction of aromatic, heteroaromatic, and aliphatic aldehydes delivered α-hydroxy ketones in high yields. This new type of catalyst proved remarkably effective for the Stetter reaction of challenging substrates such as β-alkyl-α,β-unsaturated ketones and electron-rich aromatic aldehydes in comparison to common thiazolium and triazolium salts. | en_US |
| dc.description.sponsorship | NSERC grant RGPIN-2017-06230 | en_US |
| dc.description.version | Peer Reviewed | en_US |
| dc.identifier.citation | Garapati, V. K. R.; Gravel, M. Org. Lett. 2018, 20, 6372-6375. https://doi.org/10.1021/acs.orglett.8b02636 | en_US |
| dc.identifier.doi | 10.1021/acs.orglett.8b02636 | |
| dc.identifier.uri | http://hdl.handle.net/10388/13181 | |
| dc.language.iso | en | en_US |
| dc.publisher | ACS Publications | en_US |
| dc.title | Oxazolium Salts as Organocatalysts for the Umpolung of Aldehydes | en_US |
| dc.type | Article | en_US |
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