Total Synthesis of vallartanone A
| dc.contributor.committeeMember | Ward, Dale E | |
| dc.contributor.committeeMember | Dimmock, Jonathan R | |
| dc.contributor.committeeMember | Majewski, Marek | |
| dc.creator | Lai, Leon Chun Kiu 1986- | |
| dc.date.accessioned | 2020-02-11T21:28:42Z | |
| dc.date.available | 2020-02-11T21:28:42Z | |
| dc.date.created | 2014-10 | |
| dc.date.issued | 2014-11-12 | |
| dc.date.submitted | October 2014 | |
| dc.date.updated | 2020-02-11T21:28:42Z | |
| dc.description.abstract | The research presented herein describes the first enantioselective total syntheses of vallartanone A and its (8R) epimer both starting with propanoic acid and isobutyraldehyde. The key steps involved a proline-catalyzed intermolecular aldol reaction and a second aldol reaction that proceeded with kinetic resolution. It is concluded that the absolute configuration of vallartanone A should be revised to (3S,4S,8S). | |
| dc.format.mimetype | application/pdf | |
| dc.identifier.uri | http://hdl.handle.net/10388/12661 | |
| dc.subject | vallartanone, kinetic resolution, kinetic, resolution, aldol, total synthesis | |
| dc.title | Total Synthesis of vallartanone A | |
| dc.type | Thesis | |
| dc.type.material | text | |
| thesis.degree.department | Chemistry | |
| thesis.degree.discipline | Chemistry | |
| thesis.degree.grantor | University of Saskatchewan | |
| thesis.degree.level | Masters | |
| thesis.degree.name | Master of Science (M.Sc.) |