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Biochemical and physiological aspects of obesity, high fat diet, and prolonged fasting in free-ranging polar bears

dc.contributor.committeeMemberRamsay, Malcolmen_US
dc.contributor.committeeMemberLeighton, Frederick A.en_US
dc.creatorCattet, Marcen_US
dc.date.accessioned2004-10-21T00:23:42Zen_US
dc.date.accessioned2013-01-04T05:05:34Z
dc.date.available2000-06-01T08:00:00Zen_US
dc.date.available2013-01-04T05:05:34Z
dc.date.created2000-06en_US
dc.date.issued2000-06-01en_US
dc.date.submittedJune 2000en_US
dc.description.abstractThe principle objective of this investigation was to develop an understanding of the biochemical and physiological response of free-ranging adult polar bears (Ursus maritimus) to prolonged fasting. A body condition index was developed from two measures, total body mass and straight-line body length, and was used as a covariate in the analyses of all other data. Protein and amino acid catabolism and urea synthesis were significantly lower in fasting bears when compared to feeding bears, and in fat bears when compared to lean bears. The inference from these results is that the energy metabolism in both states (fasting and fat) is one in which lipid is the predominant fuel for energy and nitrogen is conserved. Nutritional state (feeding versus fasting) had no significant effect on the plasma concentrations of non-esterified fatty acid, glycerol, and ketone bodies, or on the plasma ratio of acyl-carnitine to free carnitine. Furthermore, acetoacetate concentration was below the level of detection (en_US
dc.identifier.urihttp://hdl.handle.net/10388/etd-10212004-002342en_US
dc.language.isoen_USen_US
dc.subjectlipid metabolismen_US
dc.subjectprotein metabolismen_US
dc.subjectursus maritimusen_US
dc.subjectfastingen_US
dc.subjectpolar bears - dieten_US
dc.subjectcarbohydrate metabolismen_US
dc.titleBiochemical and physiological aspects of obesity, high fat diet, and prolonged fasting in free-ranging polar bearsen_US
dc.type.genreThesisen_US
dc.type.materialtexten_US
thesis.degree.departmentVeterinary Pathologyen_US
thesis.degree.disciplineVeterinary Pathologyen_US
thesis.degree.grantorUniversity of Saskatchewanen_US
thesis.degree.levelDoctoralen_US
thesis.degree.nameDoctor of Philosophy (Ph.D.)en_US

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