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Microbial contributions to gut development in the neonatal pig

dc.contributor.advisorVan Kessel, Andrew G.en_US
dc.contributor.committeeMemberSimko, Elemiren_US
dc.contributor.committeeMemberLaarveld, Bernarden_US
dc.contributor.committeeMemberBuchanan, Fiona C.en_US
dc.contributor.committeeMemberZijlstra, Ruurd T.en_US
dc.creatorWilling, Benjamin Peteren_US
dc.date.accessioned2007-08-28T00:44:32Zen_US
dc.date.accessioned2013-01-04T04:55:25Z
dc.date.available2008-08-30T08:00:00Zen_US
dc.date.available2013-01-04T04:55:25Z
dc.date.created2007en_US
dc.date.issued2007en_US
dc.date.submitted2007en_US
dc.description.abstractThe commensal intestinal microbiota contributes substantially to intestinal development in the early neonatal period by mechanisms that are not yet elucidated but could contribute to novel strategies to improve intestinal health. A series of gnotobiotic experiments using isolator-reared caesarian section-derived piglets inoculated at 1 d of age with selected bacteria and euthanized at 14 or 15 days of age were performed to investigate intestinal morphology, inflammation and digestive function. In Experiment 1, piglets were maintained germfree (GF), mono-associated with Escherichia coli (EC), mono-associated with Lactobacillus fermentum (LF) or conventionalized with sow feces (CV). Increased (Pen_US
dc.identifier.urihttp://hdl.handle.net/10388/etd-08282007-004432en_US
dc.language.isoen_USen_US
dc.subjecthost-microbial interactionen_US
dc.subjectcommensal bacteriaen_US
dc.subjectgnotobiotic pigen_US
dc.titleMicrobial contributions to gut development in the neonatal pigen_US
dc.type.genreThesisen_US
dc.type.materialtexten_US
thesis.degree.departmentAnimal and Poultry Scienceen_US
thesis.degree.disciplineAnimal and Poultry Scienceen_US
thesis.degree.grantorUniversity of Saskatchewanen_US
thesis.degree.levelDoctoralen_US
thesis.degree.nameDoctor of Philosophy (Ph.D.)en_US

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